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PXD034113

PXD034113 is an original dataset announced via ProteomeXchange.

Dataset Summary
Title4-HNE modification of human recombinant Dicer
DescriptionWe used mass spectrometry analysis (nanoLC-MS/MS) to map 4-HNE-modified residues of human Dicer exposed in vitro to 4-HNE in a concentration-dependent maner
HostingRepositoryPRIDE
AnnounceDate2023-11-17
AnnouncementXMLSubmission_2023-11-17_11:04:13.896.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlejandro Leyva
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-25 06:52:04ID requested
12023-11-17 11:04:14announced
Publication List
10.1093/eurheartj/ehad662;
Kiyuna LA, Candido DS, Bechara LRG, Jesus ICG, Ramalho LS, Krum B, Albuquerque RP, Campos JC, Bozi LHM, Zambelli VO, Alves AN, Campolo N, Mastrogiovanni M, Bartesaghi S, Leyva A, Dur, á, n R, Radi R, Arantes GM, Cunha-Neto E, Mori MA, Chen CH, Yang W, Mochly-Rosen D, MacRae IJ, Ferreira LRP, Ferreira JCB, 4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification. Eur Heart J, 44(44):4696-4712(2023) [pubmed]
Keyword List
submitter keyword: human Dicer,4-HNE, LC-MS/MS
Contact List
Rosario Durán
contact affiliationAnalytical Biochemistry and Proteomics Unit, IIBCE and Institut Pasteur de Montevideo
contact emailduran@pasteur.edu.uy
lab head
Alejandro Leyva
contact affiliationInstitut Pasteur de Montevideo
contact emailalejandrolp@pasteur.edu.uy
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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