PXD034074

PXD034074 is an original dataset announced via ProteomeXchange.

Title	The eWAT proteomics of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
Description	The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to proteomic study by Label-free quantitative techniques and mass spectrometry-based proteomics techniques, etc. The proteomics of mixed eWAT samples were performed in Jingjie PTM BioLab (Hangzhou) Co. Ltd (www.ptm-biolab.com.cn). The difference was determined by 1.5-fold-change criterion, FDR < 0.01.
HostingRepository	PRIDE
AnnounceDate	2022-08-11
AnnouncementXML	Submission_2022-08-11_05:25:34.734.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaojun Liu
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive; LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-25 02:10:46	ID requested
⏵ 1	2022-08-11 05:25:35	announced

Zhao W, Xu Q, Yang J, Xie X, Li C, Zhang W, Chen E, Guo Y, Gao M, Shi J, Zhang H, Yao H, Li M, Yan L, Fang F, Wu W, Liu X, Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation. iScience, 25(7):104544(2022) [pubmed]

submitter keyword: Proteomics, eWAT, Mdm2, Mice, High-fat diet

Xiaojun Liu
contact affiliation	State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College, Beijing 100005, China
contact email	xiaojunliu@ibms.pumc.edu.cn
lab head
Xiaojun Liu
contact affiliation	Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College
contact email	xiaojunliu@ibms.pumc.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD034074

PRIDE project URI

• PRIDE
  1. PXD034074
     1. Label: PRIDE project
     2. Name: The eWAT proteomics of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet