PXD034057

PXD034057 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Chronic hypoxic response in rod photoreceptors
Description	In this study, we address the underlying cause of photoreceptor degeneration by focusing on alterations in energy metabolism during chronic HIF activation. Using layer-specific proteomics, we analyzed proteome alterations in photoreceptor segments and cell bodies upon chronic HIF activation.
HostingRepository	PRIDE
AnnounceDate	2025-04-29
AnnouncementXML	Submission_2025-04-29_08:05:40.321.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Vyara Todorova
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-25 01:11:26	ID requested
⏵ 1	2025-04-29 08:05:41	announced

Publication List

Todorova V, Stauffacher MF, Ravotto L, N, ö, tzli S, Karademir D, Ebner LJA, Imsand C, Merolla L, Hauck SM, Samardzija M, Saab AS, Barros LF, Weber B, Grimm C, Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation. Mol Neurodegener, 18(1):15(2023) [pubmed]
10.1186/s13024-023-00602-x;

Todorova V, Stauffacher MF, Ravotto L, N, ö, tzli S, Karademir D, Ebner LJA, Imsand C, Merolla L, Hauck SM, Samardzija M, Saab AS, Barros LF, Weber B, Grimm C, Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation. Mol Neurodegener, 18(1):15(2023) [pubmed]

10.1186/s13024-023-00602-x;

Keyword List

submitter keyword: Mouse, hypoxia, rod photoreceptor

submitter keyword: Mouse, hypoxia, rod photoreceptor

Contact List

Christian Grimm
contact affiliation	Laboratory for Retinal Cell Biology, Departhment of Ophtalmology, University Hospital Zurich, University Zurich, Wagistrasse 14, 8952 Schlieren, Zurich, Switzerland
contact email	cgrimm@opht.uzh.ch
lab head
Vyara Todorova
contact affiliation	UZH
contact email	vyara.todorova@uzh.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD034057
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD034057

PRIDE project URI

Repository Record List

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