PXD034045

PXD034045 is an original dataset announced via ProteomeXchange.

Title	Shotgun LC-MS analysis of human serum from COVID-19 patients
Description	Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), whose outbreak in 2019 led to an ongoing pandemic with devastating consequences for the global economy and human health. According to World Health Organization, COVID-19 has affected more than 481 million people worldwide, with 6 million confirmed deaths. The joint efforts of the scientific community have undoubtedly increased the pace of production of COVID-19 vaccines, but there is still so much uncharted ground to cover regarding the mechanisms of SARS-CoV-2 infection, replication and host response. This issues can be approached by proteomics with unprecedented capacity paving the way for the development of more efficient strategies for patient care. In this study, we present a deep proteome analysis that has been performed on a series of COVID-19 patients aiming to identify proteins assessing the dynamics of the disease at different age ranges
HostingRepository	PRIDE
AnnounceDate	2022-08-11
AnnouncementXML	Submission_2022-08-11_09:26:59.204.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Estefanía Núñez
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-25 00:56:26	ID requested
⏵ 1	2022-08-11 09:26:59	announced

Nu, ñ, ez E, Orera I, Carmona-Rodr, í, guez L, Pa, ñ, o JR, V, á, zquez J, Corrales FJ, Mapping the Serum Proteome of COVID-19 Patients

Guidance for Severity Assessment. Biomedicines, 10(7):(2022) [pubmed]

submitter keyword: Human, serum,COVID-19,LC-MS

Jesús Vázquez
contact affiliation	Laboratorio de Proteómica Cardiovascular, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
contact email	jvazquez@cnic.es
lab head
Estefanía Núñez
contact affiliation	Centro Nacional de Investigaciones Cardiovasculares
contact email	enunez@cnic.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD034045

PRIDE project URI

• PRIDE
  1. PXD034045
     1. Label: PRIDE project
     2. Name: Shotgun LC-MS analysis of human serum from COVID-19 patients