PXD033991 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of lysine-lactylated substrates in gastric cancer cells |
Description | Lysine lactylation is a newly discovered post-translational modification (PTM) in histones and plays important roles in regulating gene expression. However, Kla in non-histone proteins in mammal is still unclear. Here, an analysis of lactylated proteins in gastric cancer AGS cells by using LC-MS/MS was conducted, and 2375 Kla sites on 1014 proteins were identified. |
HostingRepository | PRIDE |
AnnounceDate | 2022-08-11 |
AnnouncementXML | Submission_2022-08-11_04:13:11.210.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xianliang Ma |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | lactic acid |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-05-19 03:30:37 | ID requested | |
⏵ 1 | 2022-08-11 04:13:12 | announced | |
Publication List
Yang D, Yin J, Shan L, Yi X, Zhang W, Ding Y, Identification of lysine-lactylated substrates in gastric cancer cells. iScience, 25(7):104630(2022) [pubmed] |
Keyword List
submitter keyword: Lysine lactylation, Gastric carcinoma, Prognosis, Proteome |
Contact List
Yongbin Ding |
contact affiliation | The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China. |
contact email | njdyb@njmu.edu.cn |
lab head | |
Xianliang Ma |
contact affiliation | Micrometer Biotech |
contact email | maxianliangyxz@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033991
- Label: PRIDE project
- Name: Identification of lysine-lactylated substrates in gastric cancer cells