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PXD033991

PXD033991 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification of lysine-lactylated substrates in gastric cancer cells
DescriptionLysine lactylation is a newly discovered post-translational modification (PTM) in histones and plays important roles in regulating gene expression. However, Kla in non-histone proteins in mammal is still unclear. Here, an analysis of lactylated proteins in gastric cancer AGS cells by using LC-MS/MS was conducted, and 2375 Kla sites on 1014 proteins were identified.
HostingRepositoryPRIDE
AnnounceDate2022-08-11
AnnouncementXMLSubmission_2022-08-11_04:13:11.210.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXianliang Ma
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListlactic acid
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-19 03:30:37ID requested
12022-08-11 04:13:12announced
Publication List
Yang D, Yin J, Shan L, Yi X, Zhang W, Ding Y, Identification of lysine-lactylated substrates in gastric cancer cells. iScience, 25(7):104630(2022) [pubmed]
Keyword List
submitter keyword: Lysine lactylation, Gastric carcinoma, Prognosis, Proteome
Contact List
Yongbin Ding
contact affiliationThe First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
contact emailnjdyb@njmu.edu.cn
lab head
Xianliang Ma
contact affiliationMicrometer Biotech
contact emailmaxianliangyxz@163.com
dataset submitter
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Dataset FTP location
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