PXD033989

PXD033989 is an original dataset announced via ProteomeXchange.

Title	Serum Proteomics of Severe Fever with Thrombocytopenia Syndrome Patients
Description	Dabie bandavirus, also termed as severe fever with thrombocytopenia syndrome virus (SFTSV), was first isolated in China in 2010. At this time, the virus was found to have spread to South Korea, Japan, and other countries. A high case fatality rate is reported for SFTS, ranging from 12–50% within various sources. Several omics for clinical studies among SFTS patients as well as studies of cultured SFTSV have attempted to characterize the relevant molecular biology and epidemiology of the disease. However, a global serum proteomics analysis among SFTS patients has not yet been reported to date. Thrombocytopenia and multiple organ failure are the major immediate causes of death among SFTS patients. In this study, serum proteomic changes related to thrombocytopenia, abnormal immune response, and inflammatory activation were documented in SFTS patients. These findings provide useful information forunderstanding the clinical manifestations of SFTS.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:24:35.143.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hayoung Lee
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-19 03:24:38	ID requested
1	2022-10-13 04:53:36	announced
⏵ 2	2023-11-14 07:24:55	announced	2023-11-14: Updated project metadata.

Lee SY, Yun SH, Lee H, Lee YG, Seo G, Kim NH, Park EC, Lee CS, Kim SI, Serum proteomics of severe fever with thrombocytopenia syndrome patients. Clin Proteomics, 19(1):32(2022) [pubmed]

submitter keyword: SFTS, Serum proteomics, SFTSV, LC-MS/MS

Seung Il Kim
contact affiliation	Korea Basic Science Institute
contact email	ksi@kbsi.re.kr
lab head
Hayoung Lee
contact affiliation	Korea basic science institute
contact email	biryu32@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD033989

PRIDE project URI

• PRIDE
  1. PXD033989
     1. Label: PRIDE project
     2. Name: Serum Proteomics of Severe Fever with Thrombocytopenia Syndrome Patients