PXD033983

PXD033983 is an original dataset announced via ProteomeXchange.

Title	Proteome characterization of synovial fluid polarized healthy monocytes
Description	This project involves proteome characterization of healthy monocytes polarized (activated) with synovial fluid (SF) versus serum from patients with juvenile idiopathic arthritis (JIA). The objective is to investigate the influence of SF on monocytes at the proteome level, using serum polarized monocytes as a control. Monocytes were isolated from peripheral blood mononuclear cells of healthy donors following negative selection and were subsequently polarized overnight with 20% of a pool of either serum or SF. They were subsequently detached and used for proteome analysis.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:55:08.663.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Charlotte Welinder
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-19 02:14:40	ID requested
1	2023-07-20 10:56:37	announced
2	2023-11-14 09:02:55	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:55:09	announced	2024-10-22: Updated project metadata.

10.3389/fimmu.2023.1190018;

Schmidt T, Dahlberg A, Berthold E, Kr, ó, l P, Arve-Butler S, Ryd, é, n E, Najibi SM, Mossberg A, Bengtsson AA, Kahn F, M, å, nsson B, Kahn R, Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions. Front Immunol, 14():1190018(2023) [pubmed]

submitter keyword: Monocytes, inflammation, juvenile idiopathic arthritis, synovial fluid

Tobias Schmidt
contact affiliation	Department of Clinical Sciences Lund, Section of Rheumatology, Lund University Faculty of Medicine, Lund, Skane, Sweden
contact email	Tobias.schmidt@med.lu.se
lab head
Charlotte Welinder
contact affiliation	Dept. of Oncology, Clinical Sciences, Lund University, 221 85 Lund, Sweden
contact email	charlotte.welinder@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD033983

PRIDE project URI

• PRIDE
  1. PXD033983
     1. Label: PRIDE project
     2. Name: Proteome characterization of synovial fluid polarized healthy monocytes