PXD033961

PXD033961 is an original dataset announced via ProteomeXchange.

Title	The hepatic BCKD complex interacts with apolipoprotein E in vivo and its enzyme activity is increased in APOE4 mice
Description	APOE co-immunoprecipitation (co-IP) in liver of APOE targeted replaecement mice followed by LC−MS was used to analyse APOE protein−protein interactions and to detect as yet unknown interactor proteins.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:58:32.118.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andreas Tholey
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-18 04:47:52	ID requested
1	2023-03-10 13:01:00	announced
⏵ 2	2023-11-14 07:58:34	announced	2023-11-14: Updated project metadata.

Rueter J, Rimbach G, Treitz C, Schloesser A, L, ü, ersen K, Tholey A, Huebbe P, The mitochondrial BCKD complex interacts with hepatic apolipoprotein E in cultured cells in vitro and mouse livers in vivo. Cell Mol Life Sci, 80(3):59(2023) [pubmed]

submitter keyword: ApoE

co-immunoprecipitation

Andreas Tholey
contact affiliation	Institut für Experimentelle Medizin (IEM); Arbeitsgruppe Systematische Proteomforschung; Christian-Albrechts-Universität zu Kiel; Germany
contact email	a.tholey@iem.uni-kiel.de
lab head
Andreas Tholey
contact affiliation	Systematic Proteome Research & Bioanalytics, University of Kiel
contact email	a.tholey@iem.uni-kiel.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD033961

PRIDE project URI

• PRIDE
  1. PXD033961
     1. Label: PRIDE project
     2. Name: The hepatic BCKD complex interacts with apolipoprotein E in vivo and its enzyme activity is increased in APOE4 mice