PXD033933

PXD033933 is an original dataset announced via ProteomeXchange.

Title	Comparative analysis of N-glycoproteome differences between the mutant mld1 and wild-type Aichiasahi
Description	Protein N- glycosylation is one of the major post-translational modifications in eukaryotic cells. In plants, complex N-glycans are important for developmental programs and immune responses. In animals, Malectin selectively binds carbohydrates for diglucose and high-mannose N-glycans and forms a stable complex with an ER-resident trans-membrane protein, ribophorin I. The co-expression of malectin and ribophorin I significantly enhanced the association between malectin and a folding-defective protein and reduced its secretion; However, it was not reported that Malectin was involved in the glycosylation process in plants. Therefore, in this study, we used a proteomics approach to compare N-glycosylated protein differences between wild-type and the mutant. Our data suggest that the disruption of OsMLD1 obviously affects the N-glycosylation process, implying that OsMLD1 may play an essential role in backup glycoprotein quality control.
HostingRepository	iProX
AnnounceDate	2022-05-17
AnnouncementXML	Submission_2022-09-28_23:49:52.015.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Linlu Qi
SpeciesList	scientific name: Oryza sativa; NCBI TaxID: 4530;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-17 01:41:15	ID requested
1	2022-05-17 01:41:22	announced
⏵ 2	2022-09-28 23:49:52	announced	2022-09-29: Update publication information.

Feng H, Qiu T, Yin C, Zhao X, Xu G, Qi L, Zhang Y, Peng Y, Zhao W, The Rice Malectin Regulates Plant Cell Death and Disease Resistance by Participating in Glycoprotein Quality Control. Int J Mol Sci, 23(10):(2022) [pubmed]

submitter keyword: N-glycosylation analysis, Oryza sativa

Wensheng Zhao
contact affiliation	China Agricultural University
contact email	mppzhaws@cau.edu.cn
lab head
Linlu Qi
contact affiliation	China Agricultural University
contact email	qll2017@cau.edu.cn
dataset submitter

iProX dataset URI