PXD033849

PXD033849 is an original dataset announced via ProteomeXchange.

Title	SMARCA2, VHL Binary and Ternary Complex formation with ACBi1, PROTAC1, and PROTAC2
Description	Interrogration of impacts on Hydrogen Deuterium Exchange of ligand binding using heterobifunctional molecules ACBi1(SiTX-0038406), PROTAC1(SiTX-0038404) and PROTAC2(SiTX-0038405) on target proteins SMARCA2 and VHL both in the binary and Ternary modes.
HostingRepository	PRIDE
AnnounceDate	2022-10-12
AnnouncementXML	Submission_2022-10-12_11:52:32.387.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	DerekMacPherson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-12 08:46:31	ID requested
⏵ 1	2022-10-12 11:52:32	announced

Dataset with its publication pending

submitter keyword: HDX-MS

JesusIzaguirre
contact affiliation	VP, Advanced Simulations, Roivant Discovery, Inc
contact email	jesus.izaguirre@roivant.com
lab head
DerekMacPherson
contact affiliation	Senior Investigator at Roivant Discovery
contact email	derek.macpherson@roivant.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD033849

PRIDE project URI

• PRIDE
  1. PXD033849
     1. Label: PRIDE project
     2. Name: SMARCA2, VHL Binary and Ternary Complex formation with ACBi1, PROTAC1, and PROTAC2