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PXD033811

PXD033811 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGT-stabiligase N-terminomics technology for capturing proteolytic modifications on human cell surfaces
DescriptionHere we introduce a stabiligase technology that directly identifies neo-proteolytic epitopeson the cell surface of human cells using a glycan-tethered, engineered peptide ligase.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:50:36.291.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKaitlin Schaefer
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList6x(13)C labeled residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-11 06:01:43ID requested
12023-06-23 15:27:34announced
22023-11-14 09:01:33announced2023-11-14: Updated project metadata.
32024-10-22 05:50:37announced2024-10-22: Updated project metadata.
Publication List
Schaefer K, Lui I, Byrnes JR, Kang E, Zhou J, Weeks AM, Wells JA, Direct Identification of Proteolytic Cleavages on Living Cells Using a Glycan-Tethered Peptide Ligase. ACS Cent Sci, 8(10):1447-1456(2022) [pubmed]
10.1021/acscentsci.2c00899;
Keyword List
ProteomeXchange project tag: Human Proteome Project
submitter keyword: subtiligase protein engineering,N-terminomics, proteolysis
Contact List
Kaitlin Schaefer
contact affiliationDepartment of Pharmacology, Dr. James Wells Laboratory, University of California,San Francisco
contact emailkaitlin.schaefer@ucsf.edu
lab head
Kaitlin Schaefer
contact affiliationUniversity of California, San Francisco
contact emailkaitlin.schaefer@ucsf.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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