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PXD033779

PXD033779 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHydrophobic-hydration hydrophilic interaction (H3I) capturing intact glycopeptides
DescriptionH3I was adopted to idetify the glycosylation of bovine fetuin, human ACE2 and SARS-CoV-2 S1 proteins. Both N- and O-linked glycopeptides are successfully captured with significant enrichment rate improvements, especially for O-glycopeptides with relatively lower hydrophilicity. The majority of N- and O-glycosylation within SARS-CoV-2 S1 and hACE2 proteins are characterized simultaneously by H3I strategy, including 10 novel O-glycosylation regions with important functions in viral fusion and antibody evasion.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:56:06.224.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJing Liu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-09 05:33:38ID requested
12023-04-05 18:19:19announced
22023-11-14 08:56:06announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: hydrophobic-hydration hydrophilic interaction, glycoproteomics, mass spectrometry, hydrogen-bond network,Intact glycopeptide enrichment
Contact List
Jing Liu
contact affiliationDalian medical university
contact emailliujing8166@163.com
lab head
Jing Liu
contact affiliationDalian Medical University
contact emailliujing8166@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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