PXD033761 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Insulin Resistance in a Type 1 Diabetes Rat Model |
Description | A automated 32-plex cPILOT chemical labeling strategy was utilized to identify proteome changes in type 1 diabetes in rats. We utilized an Orbitrap Fusion Lumos mass spectrometer to analyze 8 fractions in technical triplicates where proteins were quantified using Tandem Mass Tag pro reagents (16-plex reagents) and LC-SPS-MS3 acquisiton. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-26 |
AnnouncementXML | Submission_2025-05-25_16:24:22.923.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Bailey Bowser |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-05-08 04:07:44 | ID requested | |
⏵ 1 | 2025-05-25 16:24:23 | announced | |
Publication List
Wimalarathne M, Bowser BL, Arul AB, Wilkerson-Vidal QC, David MA, Hunt EC, Gibson H, Robinson RAS, Love-Rutledge ST, Hyperinsulinemic male LEW.1WR1 rats show early signs of impaired liver metabolism. Exp Mol Pathol, 141():104955(2025) [pubmed] |
10.1016/j.yexmp.2025.104955; |
Keyword List
submitter keyword: Multiplexing, Type 1 Diabetes, Insulin Resistance,cPILOT |
Contact List
RenĂ£ Robinson |
contact affiliation | Vanderbilt University |
contact email | rena.as.robinson@vanderbilt.edu |
lab head | |
Bailey Bowser |
contact affiliation | Vanderbilt Univeristy |
contact email | bailey.bowser@vanderbilt.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD033761 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033761
- Label: PRIDE project
- Name: Insulin Resistance in a Type 1 Diabetes Rat Model