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PXD033761

PXD033761 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInsulin Resistance in a Type 1 Diabetes Rat Model
DescriptionA automated 32-plex cPILOT chemical labeling strategy was utilized to identify proteome changes in type 1 diabetes in rats. We utilized an Orbitrap Fusion Lumos mass spectrometer to analyze 8 fractions in technical triplicates where proteins were quantified using Tandem Mass Tag pro reagents (16-plex reagents) and LC-SPS-MS3 acquisiton.
HostingRepositoryPRIDE
AnnounceDate2025-05-26
AnnouncementXMLSubmission_2025-05-25_16:24:22.923.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBailey Bowser
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-08 04:07:44ID requested
12025-05-25 16:24:23announced
Publication List
Wimalarathne M, Bowser BL, Arul AB, Wilkerson-Vidal QC, David MA, Hunt EC, Gibson H, Robinson RAS, Love-Rutledge ST, Hyperinsulinemic male LEW.1WR1 rats show early signs of impaired liver metabolism. Exp Mol Pathol, 141():104955(2025) [pubmed]
10.1016/j.yexmp.2025.104955;
Keyword List
submitter keyword: Multiplexing, Type 1 Diabetes, Insulin Resistance,cPILOT
Contact List
RenĂ£ Robinson
contact affiliationVanderbilt University
contact emailrena.as.robinson@vanderbilt.edu
lab head
Bailey Bowser
contact affiliationVanderbilt Univeristy
contact emailbailey.bowser@vanderbilt.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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