PXD033724
PXD033724 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Icariside II restores vascular smooth muscle cell contractile phenotype by enhancing focal adhesion signaling pathway in rat vascular remodeling model |
Description | In this work, we investigated the pharmacological effects of ICS-II on VSMC phenotypic transition and reveal the underlying mechanisms through in vivo and in vitro experiments. Our results highlight the thera-peutic benefits of ICS-II targeting VSMC phenotypic transition and sup-port the potential of pharmacological strategies in CVD management. |
HostingRepository | iProX |
AnnounceDate | 2022-05-05 |
AnnouncementXML | Submission_2022-09-26_00:03:18.318.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hao Wen |
SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
ModificationList | S-carboxamidomethyl-L-cysteine |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-05-05 18:40:43 | ID requested | |
1 | 2022-05-05 18:41:01 | announced | |
⏵ 2 | 2022-09-26 00:03:19 | announced | 2022-09-26: Update publication information. |
Publication List
Lv J, Li X, Wu H, Li J, Luan B, Li Y, Li Y, Yang D, Wen H, Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model. Front Pharmacol, 13():897615(2022) [pubmed] |
Keyword List
submitter keyword: Icariside II, Vascular smooth muscle cell, Phenotypic transition, Vascular remodeling, Herbal medicine |
Contact List
Hao Wen | |
---|---|
contact affiliation | The First Hospital of China Medical University |
contact email | wenhao@cmu.edu.cn |
lab head | |
Hao Wen | |
contact affiliation | The First Hospital of China Medical University |
contact email | wenhao@cmu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |