PXD033724

PXD033724 is an original dataset announced via ProteomeXchange.

Title	Icariside II restores vascular smooth muscle cell contractile phenotype by enhancing focal adhesion signaling pathway in rat vascular remodeling model
Description	In this work, we investigated the pharmacological effects of ICS-II on VSMC phenotypic transition and reveal the underlying mechanisms through in vivo and in vitro experiments. Our results highlight the thera-peutic benefits of ICS-II targeting VSMC phenotypic transition and sup-port the potential of pharmacological strategies in CVD management.
HostingRepository	iProX
AnnounceDate	2022-05-05
AnnouncementXML	Submission_2022-09-26_00:03:18.318.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hao Wen
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	S-carboxamidomethyl-L-cysteine
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-05 18:40:43	ID requested
1	2022-05-05 18:41:01	announced
⏵ 2	2022-09-26 00:03:19	announced	2022-09-26: Update publication information.

Lv J, Li X, Wu H, Li J, Luan B, Li Y, Li Y, Yang D, Wen H, Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model. Front Pharmacol, 13():897615(2022) [pubmed]

submitter keyword: Icariside II, Vascular smooth muscle cell, Phenotypic transition, Vascular remodeling, Herbal medicine

Hao Wen
contact affiliation	The First Hospital of China Medical University
contact email	wenhao@cmu.edu.cn
lab head
Hao Wen
contact affiliation	The First Hospital of China Medical University
contact email	wenhao@cmu.edu.cn
dataset submitter

iProX dataset URI