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PXD033724

PXD033724 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIcariside II restores vascular smooth muscle cell contractile phenotype by enhancing focal adhesion signaling pathway in rat vascular remodeling model
DescriptionIn this work, we investigated the pharmacological effects of ICS-II on VSMC phenotypic transition and reveal the underlying mechanisms through in vivo and in vitro experiments. Our results highlight the thera-peutic benefits of ICS-II targeting VSMC phenotypic transition and sup-port the potential of pharmacological strategies in CVD management.
HostingRepositoryiProX
AnnounceDate2022-05-05
AnnouncementXMLSubmission_2022-09-26_00:03:18.318.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHao Wen
SpeciesList scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationListS-carboxamidomethyl-L-cysteine
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-05 18:40:43ID requested
12022-05-05 18:41:01announced
22022-09-26 00:03:19announced2022-09-26: Update publication information.
Publication List
Lv J, Li X, Wu H, Li J, Luan B, Li Y, Li Y, Yang D, Wen H, Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model. Front Pharmacol, 13():897615(2022) [pubmed]
Keyword List
submitter keyword: Icariside II, Vascular smooth muscle cell, Phenotypic transition, Vascular remodeling, Herbal medicine
Contact List
Hao Wen
contact affiliationThe First Hospital of China Medical University
contact emailwenhao@cmu.edu.cn
lab head
Hao Wen
contact affiliationThe First Hospital of China Medical University
contact emailwenhao@cmu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI