PXD033709 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Discrimination of tumor and normal tissues in renal cell carcinoma |
Description | Uncovering a protein abundance-based gene panel specific to clear cell Renal Cell Carcinoma (ccRCC) could provide support for the everyday clinical decision-making process. We used proteomic data to differentiate between normal kidney and ccRCC tissues. By using datasets of patients with paired normal tissue samples from gene array cohorts, we uncovered the top genes over-expressed in ccRCC. We collected surgically resected ccRCC specimens at Semmelweis University to validate the strongest genes. Differential expression was evaluated at the protein level using targeted mass spectrometry (MS). |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:45:42.433.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Aron Bartha |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-05-05 01:18:30 | ID requested | |
1 | 2023-05-10 15:16:42 | announced | |
2 | 2023-11-14 08:48:01 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 05:45:43 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.3390/ijms24054488; |
Bartha Á, Darula Z, Munk, á, csy G, Klement É, Nyir, á, dy P, Gy, ő, rffy B, Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma. Int J Mol Sci, 24(5):(2023) [pubmed] |
Keyword List
submitter keyword: targeted quantification,ccRCC, SIL |
Contact List
Balazs Gyorffy |
contact affiliation | Department of Bioinformatics, Semmelweis University |
contact email | gyorffylab@gmail.com |
lab head | |
Aron Bartha |
contact affiliation | Semmelweis Uninversity Department of Bioinformatics |
contact email | bartha.aron@med.semmelweis-univ.hu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD033709 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033709
- Label: PRIDE project
- Name: Discrimination of tumor and normal tissues in renal cell carcinoma