PXD033709

PXD033709 is an original dataset announced via ProteomeXchange.

Title	Discrimination of tumor and normal tissues in renal cell carcinoma
Description	Uncovering a protein abundance-based gene panel specific to clear cell Renal Cell Carcinoma (ccRCC) could provide support for the everyday clinical decision-making process. We used proteomic data to differentiate between normal kidney and ccRCC tissues. By using datasets of patients with paired normal tissue samples from gene array cohorts, we uncovered the top genes over-expressed in ccRCC. We collected surgically resected ccRCC specimens at Semmelweis University to validate the strongest genes. Differential expression was evaluated at the protein level using targeted mass spectrometry (MS).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:45:42.433.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aron Bartha
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-05 01:18:30	ID requested
1	2023-05-10 15:16:42	announced
2	2023-11-14 08:48:01	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:45:43	announced	2024-10-22: Updated project metadata.

10.3390/ijms24054488;

Bartha Á, Darula Z, Munk, á, csy G, Klement É, Nyir, á, dy P, Gy, ő, rffy B, Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma. Int J Mol Sci, 24(5):(2023) [pubmed]

submitter keyword: targeted quantification,ccRCC, SIL

Balazs Gyorffy
contact affiliation	Department of Bioinformatics, Semmelweis University
contact email	gyorffylab@gmail.com
lab head
Aron Bartha
contact affiliation	Semmelweis Uninversity Department of Bioinformatics
contact email	bartha.aron@med.semmelweis-univ.hu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD033709

PRIDE project URI

• PRIDE
  1. PXD033709
     1. Label: PRIDE project
     2. Name: Discrimination of tumor and normal tissues in renal cell carcinoma