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PXD033709

PXD033709 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiscrimination of tumor and normal tissues in renal cell carcinoma
DescriptionUncovering a protein abundance-based gene panel specific to clear cell Renal Cell Carcinoma (ccRCC) could provide support for the everyday clinical decision-making process. We used proteomic data to differentiate between normal kidney and ccRCC tissues. By using datasets of patients with paired normal tissue samples from gene array cohorts, we uncovered the top genes over-expressed in ccRCC. We collected surgically resected ccRCC specimens at Semmelweis University to validate the strongest genes. Differential expression was evaluated at the protein level using targeted mass spectrometry (MS).
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:45:42.433.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAron Bartha
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-05 01:18:30ID requested
12023-05-10 15:16:42announced
22023-11-14 08:48:01announced2023-11-14: Updated project metadata.
32024-10-22 05:45:43announced2024-10-22: Updated project metadata.
Publication List
10.3390/ijms24054488;
Bartha Á, Darula Z, Munk, á, csy G, Klement É, Nyir, á, dy P, Gy, ő, rffy B, Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma. Int J Mol Sci, 24(5):(2023) [pubmed]
Keyword List
submitter keyword: targeted quantification,ccRCC, SIL
Contact List
Balazs Gyorffy
contact affiliationDepartment of Bioinformatics, Semmelweis University
contact emailgyorffylab@gmail.com
lab head
Aron Bartha
contact affiliationSemmelweis Uninversity Department of Bioinformatics
contact emailbartha.aron@med.semmelweis-univ.hu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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