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PXD033655

PXD033655 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of patients with advanced triple-negative breast cancer
DescriptionIn the later-line setting or for patients with PD-L1-negative tumors, immunotherapy-based regimens remain ineffective against advanced triple-negative breast cancer (TNBC). In this multicentered phase II trial (NCT04303741), 46 patients with pretreated advanced TNBC were enrolled to receive camrelizumab 200 mg (day 1), and apatinib 250 mg daily, plus eribulin 1.4 mg/m2 (day 1 and 8) on a 21-day cycle until progression, or unacceptable toxicity. We performed correlation analysis between the patient's baseline protein expression level and curative effect.
HostingRepositoryiProX
AnnounceDate2022-05-04
AnnouncementXMLSubmission_2022-06-09_00:53:58.343.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhenluan Tian
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-04 18:50:56ID requested
12022-05-04 18:51:48announced
22022-06-09 00:53:59announced2022-06-09: Update publication information.
Publication List
Liu J, Wang Y, Tian Z, Lin Y, Li H, Zhu Z, Liu Q, Su S, Zeng Y, Jia W, Yang Y, Xu S, Yao H, Jiang W, Song E, Multicenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer. Nat Commun, 13(1):3011(2022) [pubmed]
Keyword List
submitter keyword: Breast cancer
Contact List
Jieqiong Liu
contact affiliationGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
contact emailliujieqiong01@163.com
lab head
Zhenluan Tian
contact affiliationGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
contact email1339087943@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI