PXD033617

PXD033617 is an original dataset announced via ProteomeXchange.

Title	Ethinylestradiol in COC has broader effect on serum proteome compared with estradiol valerate - a randomized trial: LOW ABUNDANCE PROTEINS
Description	Ethinylestradiol (EE)-based combined oral contraceptives (COC) have multiple beneficial effects besides contraception, but they also cause certain unfavorable health outcomes. They interfere, for example, with metabolism, inflammation, hepatic protein synthesis, and blood coagulation. COCs containing natural estrogens have recently been developed, yet little is known about their non-contraceptive effects compared to conventional EE-based COCs. The aim of the study was to analyze the serum proteome during three different treatments: EE+dienogest (DNG), estradiol valerate (EV)+DNG, and DNG only.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:56:25.375.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD033617
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Sakari Joenväärä
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-04 10:07:45	ID requested
1	2022-11-25 06:24:30	announced
⏵ 2	2023-11-14 08:56:25	announced	2023-11-14: Updated project metadata.

10.6019/PXD033617;

submitter keyword: Estradiol valerate, COC, ethinylestradiol, serum proteome

Risto Renkonen
contact affiliation	1) Haartman Institute, University of Helsinki, Helsinki, Finland. 2) HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.
contact email	risto.renkonen@helsinki.fi
lab head
Sakari Joenväärä
contact affiliation	Helsinki University
contact email	sakari.joenvaara@helsinki.fi
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD033617
     1. Label: PRIDE project
     2. Name: Ethinylestradiol in COC has broader effect on serum proteome compared with estradiol valerate - a randomized trial: LOW ABUNDANCE PROTEINS