PXD033579

PXD033579 is an original dataset announced via ProteomeXchange.

Title	SILAC proteomic analysis of secreted proteins from PLC cells expressing EV or PRSS35
Description	Since PRSS35 only exhibited tumor suppressive effects in mice, but not in the cultured cells, we speculated that some factors in the microenvironment are affected by PRSS35. To explore this possibility, we performed SILAC proteomic analysis in conjunction with RNA sequencing to identify secreted proteins that decreased in accumulation, but not in transcription level, in the culture medium of PRSS35 overexpressing PLC cells.
HostingRepository	PRIDE
AnnounceDate	2023-02-15
AnnouncementXML	Submission_2023-02-14_21:52:37.288.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	TingWang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	isotope labeled residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-04 09:01:00	ID requested
⏵ 1	2023-02-14 21:52:37	announced

Dataset with its publication pending

submitter keyword: EV, PRSS35, PLC,secreted proteins

HuafengZhang
contact affiliation	University of Science and Technology of China
contact email	hzhang22@ustc.edu.cn
lab head
TingWang
contact affiliation	University of Science and Technology of China
contact email	Tkane@mail.ustc.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD033579

PRIDE project URI

• PRIDE
  1. PXD033579
     1. Label: PRIDE project
     2. Name: SILAC proteomic analysis of secreted proteins from PLC cells expressing EV or PRSS35