<<< Full experiment listing


PXD033527 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSpatial proteomics of selinexor, MK-2206 and combination response in AML cells
DescriptionIn order to characterize the dynamics of proteins between different cellular compartments in response to selinexor (XPO1 inhibitor), MK-2206 (Akt inhibitor) an the combination i AML cells, we treated MV4-11 and PL-21 cells for 6 hours with DMSO, 1 uM selinexor, 1 uM MK-2206 or the combination. Each condition was performed in 4 biological bio-reps.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKristina Bennet Emdal
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-28 01:31:08ID requested
12022-08-07 23:13:26announced
Publication List
Keyword List
submitter keyword: Human, AML, LC-MS/MS, spatial proteomics
Contact List
Jesper V. Olsen
contact affiliationProteomics program, The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark
contact emailjesper.olsen@cpr.ku.dk
lab head
Kristina Bennet Emdal
contact affiliationNNF Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen.
contact emailkristina.emdal@cpr.ku.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD033527
PRIDE project URI
Repository Record List
[ + ]