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PXD033527

PXD033527 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSpatial proteomics of selinexor, MK-2206 and combination response in AML cells
DescriptionIn order to characterize the dynamics of proteins between different cellular compartments in response to selinexor (XPO1 inhibitor), MK-2206 (Akt inhibitor) an the combination i AML cells, we treated MV4-11 and PL-21 cells for 6 hours with DMSO, 1 uM selinexor, 1 uM MK-2206 or the combination. Each condition was performed in 4 biological bio-reps.
HostingRepositoryPRIDE
AnnounceDate2022-08-08
AnnouncementXMLSubmission_2022-08-07_23:13:26.488.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKristina Bennet Emdal
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-28 01:31:08ID requested
12022-08-07 23:13:26announced
Publication List
10.1016/J.CELREP.2022.111177;
Keyword List
submitter keyword: Human, AML, LC-MS/MS, spatial proteomics
Contact List
Jesper V. Olsen
contact affiliationProteomics program, The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark
contact emailjesper.olsen@cpr.ku.dk
lab head
Kristina Bennet Emdal
contact affiliationNNF Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen.
contact emailkristina.emdal@cpr.ku.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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