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PXD033525

PXD033525 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe salivary proteome in relation to oral mucositis in autologous hematopoietic stem cell transplantation recipients: a labelled and label-free proteomics approach -DIAdata
DescriptionDecreased salivary flow rates and/or changes in protein composition reported after autologous hematopoietic stem cell transplantation (ASCT) reduces the protective function of saliva. This might be associated with the development of oral mucositis (OM), an inflammation of the oral mucosa as a result of chemotherapy before ASCT which affects patients, quality of life and risk factor for systemic infections. In this study, a TMT-labelled proteomics experiment, a label-free quantification (LFQ) proteomics experiment and a DIA-MS proteomics experiment were used to identify differences in the salivary proteome between patients with ulcerative OM (uOM; WHO score 2) and those without (nOM).
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:05:27.785.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAn Staes
SpeciesList scientific name: human oral bacteria ensemble; NCBI TaxID: 150596; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-28 01:30:30ID requested
12023-07-10 04:26:46announced
22023-11-14 07:05:28announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: LC-MS, TMT-labelled proteomics,TMT-MS, Label-free quantification, Saliva,Oral Mucositis, Autologous hematopoietic stem cell transplantation, Multiple Myeloma,DIA-MS
Contact List
Nicole M.A. Blijlevens
contact affiliationRadboud university medical center, Radboud Institute for Health Sciences, Department of Hematology The Netherlands
contact emailNicole.Blijlevens@radboudumc.nl
lab head
An Staes
contact affiliationMedical Protein Chemistry
contact emailan.staes@vib-ugent.be
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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