PXD033522

PXD033522 is an original dataset announced via ProteomeXchange.

Title	Complexome profiling of mitochondria to study NDUFAF1 mediated complex I assembly in Yarrowia lipolytica
Description	The aerobic yeast Yarrowia lipolytica is an established model organism to study mitochondrial protein complexes. Here we performed a complexome analysis of intact mitochondria to study the function of NDUFAF1 in the assembly of respiratory complex I. In the ndufaf1 deletion strain the PD module of the membrane arm accumulated but mature complex I was virtually absent.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:56:07.966.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ilka Wittig
SpeciesList	scientific name: Yarrowia lipolytica (Candida lipolytica); NCBI TaxID: 4952;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-04-28 01:23:21	ID requested
1	2022-12-21 05:54:07	announced
⏵ 2	2023-11-14 08:56:08	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: protein complexes,Assembly

Volker Zickermann
contact affiliation	Institute of Biochemistry II, University Hospital, Goethe University, Frankfurt am Main, Germany.
contact email	Zickermann@med.uni-frankfurt.de
lab head
Ilka Wittig
contact affiliation	Functional Proteomics, Goethe University, Frankfurt am Main , Germany
contact email	wittig@med.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD033522

PRIDE project URI

• PRIDE
  1. PXD033522
     1. Label: PRIDE project
     2. Name: Complexome profiling of mitochondria to study NDUFAF1 mediated complex I assembly in Yarrowia lipolytica