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PXD033342

PXD033342 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleN-linked glycan analysis of native SARS-CoV-2 Delta variant Spike
DescriptionThe SARS-CoV-2 Delta variant is more contagious than WT and causes severe symptoms.To understand the elevated fusogenicity of Delta, we used LC-MS/MS to characterize the site specific N-linked glycan of spike protein in SARS-CoV-2 Delta variant virions.The glycan analysis revealed increased oligomannose-type glycosylation of native Delta spike over that of the Wuhan-Hu-1 spike.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:46:47.864.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYutong Song
SpeciesList scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: 2697049;
ModificationListcomplex glycosylation
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-21 06:47:29ID requested
12023-05-10 13:33:37announced
22023-11-14 08:46:51announced2023-11-14: Updated project metadata.
Publication List
Song Y, Yao H, Wu N, Xu J, Zhang Z, Peng C, Li S, Kong W, Chen Y, Zhu M, Wang J, Shi D, Zhao C, Lu X, Echavarr, í, a Galindo M, Li S, In situ architecture and membrane fusion of SARS-CoV-2 Delta variant. Proc Natl Acad Sci U S A, 120(18):e2213332120(2023) [pubmed]
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19
submitter keyword: LC-MS/MS,SARS-CoV-2,N-linked glycan
Contact List
Sai Li
contact affiliationSchool of Life Sciences, Tsinghua University, Beijing, China
contact emailsai@tsinghua.edu.cn
lab head
Yutong Song
contact affiliationstudent
contact emailsyt18@mails.tsinghua.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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