PXD033293 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis neutrophils from COVID-19 patients |
Description | To go further insight into the involvement of neutrophils in COVID-19 clinical expression, we performed a proteomic analysis of this blood cell type in COVID-19 patients and two non-infected SARS-CoV-2 control groups composed of healthy subjects and ARDS patients hospitalized in intensive care unit (ICU) respectively. All patients were from Guadeloupe and represent a homogeneous population. We have performed a quantitative proteomic study of neutrophiles from French hot spot COVID region, Guadeloupe, confirming the activation of type I IFN pathway and in some target of IFN as TAP proteins, specifically in COVID patients, but not in hospitalized ARDS non-COVID patients and described modification of the NET proteome potentially associated with ARDS. |
HostingRepository | PRIDE |
AnnounceDate | 2022-07-27 |
AnnouncementXML | Submission_2022-07-27_06:38:50.248.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Emilie-Fleur GAUTIER |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-19 03:16:56 | ID requested | |
⏵ 1 | 2022-07-27 06:38:50 | announced | |
Publication List
Romana M, Leduc M, Hermand P, Bruce J, Gautier EF, Martino F, Garnier Y, Baccini V, Le Van Kim C, Proteomic analysis of neutrophils from patients with COVID-19. Br J Haematol, 199(1):61-64(2022) [pubmed] |
Keyword List
submitter keyword: Neutrophil, Labelfree, COVID-19, TIMS-TOF |
Contact List
Emilie-Fleur Gautier |
contact affiliation | Laboratoire d’Excellence GR-Ex, Paris, France 3P5 Proteom’IC facility, Université Paris Cité, Institut Cochin, INSERM, CNRS, F-75014 PARIS, France |
contact email | ef.gautier.upd@gmail.com |
lab head | |
Emilie-Fleur GAUTIER |
contact affiliation | Plateforme Proteomique 3P5, Université Paris Descartes, Inserm U1016, Institut Cochin, Cnrs UMR8104, France |
contact email | ef.gautier.upd@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033293
- Label: PRIDE project
- Name: Proteomic analysis neutrophils from COVID-19 patients