PXD033293

PXD033293 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis neutrophils from COVID-19 patients
Description	To go further insight into the involvement of neutrophils in COVID-19 clinical expression, we performed a proteomic analysis of this blood cell type in COVID-19 patients and two non-infected SARS-CoV-2 control groups composed of healthy subjects and ARDS patients hospitalized in intensive care unit (ICU) respectively. All patients were from Guadeloupe and represent a homogeneous population. We have performed a quantitative proteomic study of neutrophiles from French hot spot COVID region, Guadeloupe, confirming the activation of type I IFN pathway and in some target of IFN as TAP proteins, specifically in COVID patients, but not in hospitalized ARDS non-COVID patients and described modification of the NET proteome potentially associated with ARDS.
HostingRepository	PRIDE
AnnounceDate	2022-07-27
AnnouncementXML	Submission_2022-07-27_06:38:50.248.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Emilie-Fleur GAUTIER
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-04-19 03:16:56	ID requested
⏵ 1	2022-07-27 06:38:50	announced

Romana M, Leduc M, Hermand P, Bruce J, Gautier EF, Martino F, Garnier Y, Baccini V, Le Van Kim C, Proteomic analysis of neutrophils from patients with COVID-19. Br J Haematol, 199(1):61-64(2022) [pubmed]

submitter keyword: Neutrophil, Labelfree, COVID-19, TIMS-TOF

Emilie-Fleur Gautier
contact affiliation	Laboratoire d’Excellence GR-Ex, Paris, France 3P5 Proteom’IC facility, Université Paris Cité, Institut Cochin, INSERM, CNRS, F-75014 PARIS, France
contact email	ef.gautier.upd@gmail.com
lab head
Emilie-Fleur GAUTIER
contact affiliation	Plateforme Proteomique 3P5, Université Paris Descartes, Inserm U1016, Institut Cochin, Cnrs UMR8104, France
contact email	ef.gautier.upd@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD033293

PRIDE project URI

• PRIDE
  1. PXD033293
     1. Label: PRIDE project
     2. Name: Proteomic analysis neutrophils from COVID-19 patients