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PXD033178

PXD033178 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleWW domain activated extracellular vesicles (WAEV) proteome
DescriptionExtracellular vesicles (EVs), spherical nano-sized lipid-bilayer vesicular structure, is produced from host cells, and widely studied in microbiology, neurobiology, and bioengineering as drug delivery. Here, we report the new vaccine platform using a novel type of EVs, WW domain activated extracellular vesicles (WAEV). Our proteomics result showed that WAEV was activated by the WW domain independently, and distinct from the existing exosome.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:17:47.113.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSengjin Choi
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-12 05:29:04ID requested
12023-01-30 11:24:56announced
22023-11-14 08:17:48announced2023-11-14: Updated project metadata.
Publication List
Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q, Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles. Sci Adv, 9(4):eade2708(2023) [pubmed]
Keyword List
submitter keyword: Vaccine, WW domain,Extracellular vesicles
Contact List
Quan Lu
contact affiliationHarvard T.H. Chan school of public health
contact emailqlu@hsph.harvard.edu
lab head
Sengjin Choi
contact affiliationHarvard T.H. Chan School of Public Health
contact emailsengjinchoi@hsph.harvard.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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