PXD033164 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multi-omics approach to characterize sex-specific metabolic alterations in triple-transgenic Alzheimer's mouse brain |
Description | We aimed to characterise alterations in metabolic pathways and proteome composition in a mouse model of Alzheimer disease (AD). We specifically aimed to evaluate how these differences may be sex-specific by integrative multi-omics analysis (metabolites, lipids, proteins). |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:43:10.650.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Manfredo Quadroni |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-12 01:57:26 | ID requested | |
1 | 2023-03-11 07:27:02 | announced | |
⏵ 2 | 2023-11-14 08:43:14 | announced | 2023-11-14: Updated project metadata. |
Publication List
Strefeler A, Jan M, Quadroni M, Teav T, Rosenberg N, Chatton JY, Guex N, Gallart-Ayala H, Ivanisevic J, Molecular insights into sex-specific metabolic alterations in Alzheimer's mouse brain using multi-omics approach. Alzheimers Res Ther, 15(1):8(2023) [pubmed] |
Keyword List
submitter keyword: proteomics, brain, metabolomics, TGAD mouse, data-independent acquisition,Alzheimer's disease |
Contact List
Julijana Ivanisevic |
contact affiliation | University of Lausanne Metabolomics Platform (MEP) Quartier UNIL-CHUV Rue du Bugnon 19 CH-1005 Lausanne |
contact email | Julijana.Ivanisevic@unil.ch |
lab head | |
Manfredo Quadroni |
contact affiliation | University of Lausanne |
contact email | manfredo.quadroni@unil.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD033164 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033164
- Label: PRIDE project
- Name: Multi-omics approach to characterize sex-specific metabolic alterations in triple-transgenic Alzheimer's mouse brain