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PXD033150

PXD033150 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLIS1 RNA binding orchestartes the mechanosensitive properties of embryonic stem cells in AGO2 dependent and independent ways.
DescriptionLIS1 immunoprecipitation in nuclear and cytoplasmic fractions of LIS1 Floxed/-, OE and WT embryonic stem cells. To identify AGO2 dependent and independent interactions LIS1 was immunoprecipitated in AGO1-4 knockout and doxycycline induced AGO2 mouse embryonic stem cells.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_09:03:07.688.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD033150
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterAditya Kshirsagar
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-11 02:47:54ID requested
12023-07-20 11:16:50announced
22023-11-14 09:03:11announced2023-11-14: Updated project metadata.
Publication List
Kshirsagar A, Doroshev SM, Gorelik A, Olender T, Sapir T, Tsuboi D, Rosenhek-Goldian I, Malitsky S, Itkin M, Argoetti A, Mandel-Gutfreund Y, Cohen SR, Hanna JH, Ulitsky I, Kaibuchi K, Reiner O, LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways. Nat Commun, 14(1):3293(2023) [pubmed]
10.6019/PXD033150;
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: OE, Dox.AGO2, AGO1-4 KO, nuclear and cytoplasmic fractions, Flox/-,WT, mouse embyonic stem cells,LIS1 IP
Contact List
Orly Reiner
contact affiliationDepartments of Molecular Genetics and Molecular Neuroscience
contact emailorly.reiner@weizmann.ac.il
lab head
Aditya Kshirsagar
contact affiliationWeizmann Institute of Science
contact emailadityag3vtp@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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