PXD033133

PXD033133 is an original dataset announced via ProteomeXchange.

Title	Differentially expressed proteins between WT testis and Cfap70-KO testis
Description	We applied iTRAQ Quantification Proteomics to explore Differentially expressed proteins between WT testis and Cfap70-KO testis. In this iTRAQ quantification project,there were 6 Mus_musculus samples named C_1, C_2, C_3, K_1, K_2, K_3 and we did 1 technical duplicate experiments. Totally 480850 spectrums were generated, 38748 peptides and 6734 proteins were identified with 1% FDR. proteins with 1.2 fold change(mean value of all comparison groups) and P-value(t-test of all comparision groups) less than 0.05 were defined as differentially expressed proteins.
HostingRepository	iProX
AnnounceDate	2022-04-11
AnnouncementXML	Submission_2023-07-17_19:41:20.570.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Suren Chen
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	iTRAQ8plex reporter+balance reagent acylated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2022-04-10 21:40:15	ID requested
1	2022-04-10 21:40:30	announced
⏵ 2	2023-07-17 19:41:21	announced	2023-07-18: Update publication information.

Jin HJ, Wang JL, Geng XY, Wang CY, Wang BB, Chen SR, CFAP70 is a solid and valuable target for the genetic diagnosis of oligo-astheno-teratozoospermia in infertile men. EBioMedicine, 93():104675(2023) [pubmed]

submitter keyword: Cfap70-KO testis

Suren Chen
contact affiliation	College of Life Sciences, Beijing Normal University, China
contact email	chensr@bnu.edu.cn
lab head
Suren Chen
contact affiliation	College of Life Sciences, Beijing Normal University, China
contact email	chensr@bnu.edu.cn
dataset submitter

iProX dataset URI