PXD033072

PXD033072 is an original dataset announced via ProteomeXchange.

Title	HDX-MS Analysis of the Rab3GAP1/Rab3GAP2
Description	An HDX-MS analysis of the Rab3GAP1 and Rab3GAP2 subunit interface, and the binding interface between Rab18 and the full Rab3GAP1/2 complex.
HostingRepository	PRIDE
AnnounceDate	2025-03-10
AnnouncementXML	Submission_2025-03-10_12:08:19.105.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	John Burke
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	impact HD

Revision	Datetime	Status	ChangeLog Entry
0	2022-04-07 03:37:57	ID requested
⏵ 1	2025-03-10 12:08:20	announced

10.1038/s41467-025-55828-8;

Fairlie GMJ, Nguyen KM, Nam SE, Shaw AL, Parson MAH, Shariati HR, Wang X, Jenkins ML, Gong M, Burke JE, Yip CK, Biochemical and structural characterization of Rab3GAP reveals insights into Rab18 nucleotide exchange activity. Nat Commun, 16(1):479(2025) [pubmed]

submitter keyword: HDX-MS, Rab18, Rab3GAP2, Rab3GAP1

Dr. John E. Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
lab head
John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD033072

PRIDE project URI

• PRIDE
  1. PXD033072
     1. Label: PRIDE project
     2. Name: HDX-MS Analysis of the Rab3GAP1/Rab3GAP2