PXD032929 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | HDX-MS analysis of the mechanism of AKT1 inhibitor binding |
Description | Analysis of AKT1 inhibitor binding using HDX-MS . |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:42:22.022.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | John Burke |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | impact HD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-02 13:20:30 | ID requested | |
1 | 2024-10-08 12:44:49 | announced | |
⏵ 2 | 2024-10-22 05:42:22 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1016/j.str.2023.01.007; |
Shaw AL, Parson MAH, Truebestein L, Jenkins ML, Leonard TA, Burke JE, ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1. Structure, 31(3):343-354.e3(2023) [pubmed] |
Keyword List
submitter keyword: HDX-MS, AKT1, AKT DrLink, AKT DA |
Contact List
Dr. John E. Burke |
contact affiliation | University of Victoria |
contact email | jeburke@uvic.ca |
lab head | |
John Burke |
contact affiliation | University of Victoria |
contact email | jeburke@uvic.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD032929 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD032929
- Label: PRIDE project
- Name: HDX-MS analysis of the mechanism of AKT1 inhibitor binding