PXD032750
PXD032750 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | E3 ligase regulates FAM134B ubiquitination |
Description | FAM134B is a reticulon-homology domain (RHD)-containing protein that participates in membrane-shaping of the endoplasmic reticulum (ER)8 13. It also functions as a mammalian ER-phagy receptor, mediating the fragmentation and selective degradation of ER sheets in multiple cell types8. However, little is known about the molecular and biophysical mechanisms that control and/or switch between these two FAM134B functions. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_09:01:22.341.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Adriana Covarrubias-Pinto |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | ubiquitinylated lysine; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-03-23 07:40:51 | ID requested | |
1 | 2023-06-19 06:49:55 | announced | |
⏵ 2 | 2023-11-14 09:01:25 | announced | 2023-11-14: Updated project metadata. |
Publication List
Gonz, á, lez A, Covarrubias-Pinto A, Bhaskara RM, Glogger M, Kuncha SK, Xavier A, Seemann E, Misra M, Hoffmann ME, Br, ä, uning B, Balakrishnan A, Qualmann B, D, ö, tsch V, Schulman BA, Kessels MM, H, ü, bner CA, Heilemann M, Hummer G, Diki, ć I, Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature, 618(7964):394-401(2023) [pubmed] |
Keyword List
submitter keyword: Venus AMFR FAM134B BASAL TORIN1 |
Contact List
Ivan Dikic | |
---|---|
contact affiliation | Institute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Straße 15, 60438 Frankfurt am Main, Germany |
contact email | dikic@biochem2.uni-frankfurt.de |
lab head | |
Adriana Covarrubias-Pinto | |
contact affiliation | Goethe University |
contact email | CovarrubiasPinto@med.uni-frankfurt.de |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD032750 |
PRIDE project URI |
Repository Record List
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