PXD032719

PXD032719 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis of dental pulp stem cell-derived exosomes
Description	In order to examine the proteomics of exosomes derived from DPSCs under hypoxia (Hypo-Exos) and the mechanism underlying the angiogenic effect of DPSC-Exos, iTRAQ-based proteomics analysis and bioinformatic analysis were performed to investigate proteome profile differences between exosomes derived from DPSCs under normoxia (Nor-Exos) and Hypo-Exos.7114 peptides and 1792 proteins were identified from the Hypo-Exos samples with a 1% FDR. Compared with the control group, 39 proteins were upregulated and 40 proteins were downregulated in Hypo-Exos.
HostingRepository	PRIDE
AnnounceDate	2022-05-20
AnnouncementXML	Submission_2022-05-20_08:36:33.527.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xuehong Xian
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-23 02:57:10	ID requested
⏵ 1	2022-05-20 08:36:34	announced

Li B, Xian X, Lin X, Huang L, Liang A, Jiang H, Gong Q, Hypoxia Alters the Proteome Profile and Enhances the Angiogenic Potential of Dental Pulp Stem Cell-Derived Exosomes. Biomolecules, 12(4):(2022) [pubmed]

submitter keyword: dental pulp stem cells，exosomes，hypoxia

Qimei Gong
contact affiliation	Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou
contact email	gongqim@mail.sysu.edu.cn
lab head
Xuehong Xian
contact affiliation	Foshan Stomatological Hospital, Foshan University
contact email	xianxuehong@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD032719

PRIDE project URI

• PRIDE
  1. PXD032719
     1. Label: PRIDE project
     2. Name: Proteomic Analysis of dental pulp stem cell-derived exosomes