PXD032665

PXD032665 is an original dataset announced via ProteomeXchange.

Title	Quantitative Proteomics Analysis to Assess Protein Expression Levels in the Ovaries of Pubescent Goats
Description	Herein we identified 301 (176 up- and 125 downregulated) differentially abundant proteins (DAPs) in the ovaries of pubertal and prepubertal Anhui white goats (P < 0.05) using quantitative proteomics techniques based on LC–MS/MS and iTRAQ. Gene ontology functional enrichment analysis revealed that several DAPs enriched in biological processes were related to cellular process, biological regulation, metabolic process, and response to stimulus. Further, Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis indicated that DAPs were enriched in olfactory translation, glutathione metabolism, and calcium signaling pathways.
HostingRepository	PRIDE
AnnounceDate	2022-08-12
AnnouncementXML	Submission_2022-08-12_00:10:35.884.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ping Qin
SpeciesList	scientific name: Capra hircus; NCBI TaxID: 9925;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-20 15:29:36	ID requested
⏵ 1	2022-08-12 00:10:36	announced

Qin P, Ye J, Gong X, Yan X, Lin M, Lin T, Liu T, Li H, Wang X, Zhu Y, Li X, Liu Y, Li Y, Ling Y, Zhang X, Fang F, Quantitative proteomics analysis to assess protein expression levels in the ovaries of pubescent goats. BMC Genomics, 23(1):507(2022) [pubmed]

submitter keyword: Proteomics, iTRAQ, LC–MS/MS, pubertal onset, differentially abundant proteins, PPI network, Anhui white goats

Fang Fugui
contact affiliation	Anhui Agricultural University,China
contact email	fgfang@ahau.edu.cn
lab head
Ping Qin
contact affiliation	Anhui Agricultural University
contact email	qinping1996@163.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD032665
     1. Label: PRIDE project
     2. Name: Quantitative Proteomics Analysis to Assess Protein Expression Levels in the Ovaries of Pubescent Goats