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PXD032301

PXD032301 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe mouse kidney macrophage proteome
DescriptionMacrophages are innate immune cells that play crucial roles in dampening inflammation and maintaining tissue homeostasis. Macrophages are influenced by their tissue microenvironment, but it is still unclear how these cells contribute to distinct extracellular matrix compartments within the kidney. In this project, we defined three transcriptionally and phenotypically distinct kidney macrophage subsets that express transcripts and proteins for extracellular matrix at steady state, indicating a potential and novel role in maintaining or repairing tissue integrity.
HostingRepositoryPRIDE
AnnounceDate2026-02-02
AnnouncementXMLSubmission_2026-02-02_06:34:01.824.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMychel Morais
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-03-15 03:35:54ID requested
12026-02-02 06:34:02announced
Publication List
10.1016/J.MATBIO.2024.02.002;
Keyword List
submitter keyword: Macrophage, Extracellular matrix enrichment, Q Exactive Hybrid Quadrupole-Orbitrap, FACS, mouse, Tandem mass spectrometry,Kidney
Contact List
Rachel Lennon
contact affiliationWellcome Trust Centre for Cell-Matrix Research. University of Manchester. Manchester. United Kingdom
contact emailrachel.lennon@manchester.ac.uk
lab head
Mychel Morais
contact affiliationThe University of Manchester
contact emailmychel.morais@manchester.ac.uk
dataset submitter
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Dataset FTP location
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PRIDE project URI
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