PXD032275

PXD032275 is an original dataset announced via ProteomeXchange.

Title	monoclonal antibody NIST8671 LC-MS/MS
Description	The characteristics of monoclonal antibodies (mAbs) cohering various function effectors shows great expectation in therapy. Glycosylation, one of the common post-translational modifications, deeply influences the cohesion. It is necessary to grasp monosaccharide composition/sequence and glycan structures in mAbs. There have been comprehensive mass spectrometry characterization of N-glycosylation of mAbs, and monosaccharide compositions are deduced according to known biosynthetic rules. Our recently developed intact N-glycopeptide search engine GPSeeker has made unambiuous structure-specific characterization of N-glycosylation possible with structure-diagnostic fragment ions from selective fragmentattion of N-glycan moieties.
HostingRepository	PRIDE
AnnounceDate	2022-04-14
AnnouncementXML	Submission_2022-04-14_07:00:30.799.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bi Ming
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-14 10:00:50	ID requested
⏵ 1	2022-04-14 07:00:31	announced

Bi M, Bai B, Tian Z, Glycoproteomics Characterization of NIST Monoclonal Antibody Reference Material 8671. J Proteome Res, 21(5):1276-1284(2022) [pubmed]

submitter keyword: monocloanl antibody NIST8671

Zhixin Tian
contact affiliation	School of Chemical Science & Engineering, Tongji University, Shanghai 200092, China
contact email	zhixintian@tongji.edu.cn
lab head
Bi Ming
contact affiliation	tongji university
contact email	1910807@tongji.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD032275

PRIDE project URI

• PRIDE
  1. PXD032275
     1. Label: PRIDE project
     2. Name: monoclonal antibody NIST8671 LC-MS/MS