PXD032266
PXD032266 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | DIA analysis of paired primary and recurrent breast cancers |
Description | Molecular profiling of breast cancer has achieved great depth in defining the mutational landscapes and molecular profiles of primary tumors, though little is still known regarding cancer evolution into a recurrence. Proteogenomic workflows are particularly useful in defining the multi-layered biology of complex diseases by combining genomic, transcriptomic, and proteomic technologies so to inform not only on mutational processes, but also on their repercussion at the effector level, proteins. We employed our recently developed proteogenomic workflow to analyze a cohort of 27 primary breast cancers and their matched loco-regional recurrences by whole genome sequencing, RNA sequencing, and mass spectrometry. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_07:46:32.524.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tommaso De Marchi |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-03-14 09:46:43 | ID requested | |
1 | 2023-02-03 15:45:41 | announced | |
⏵ 2 | 2023-11-14 07:46:33 | announced | 2023-11-14: Updated project metadata. |
Publication List
De Marchi T, Pyl PT, Sj, ö, str, ö, m M, Reinsbach SE, DiLorenzo S, Nystedt B, Tran L, Pekar G, W, ä, rnberg F, Fredriksson I, Malmstr, ö, m P, Fern, ö M, Malmstr, ö, m L, Malmst, ö, m J, Nim, é, us E, Proteogenomics decodes the evolution of human ipsilateral breast cancer. Commun Biol, 6(1):139(2023) [pubmed] |
Keyword List
submitter keyword: primary, DIA, recurrence,breast cancer |
Contact List
Emma Nimeus | |
---|---|
contact affiliation | Division of Surgery, Oncology, and Pathology, Department of Clinical Sciences, Lund University, Solvegatan 19, SE-22362, Lund, Sweden. Department of Surgery, Skåne University Hospital, Lund, Sweden. |
contact email | emma.nimeus@med.lu.se |
lab head | |
Tommaso De Marchi | |
contact affiliation | Lund University |
contact email | tommaso.de_marchi@med.lu.se |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD032266 |
PRIDE project URI |
Repository Record List
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