PXD032167

PXD032167 is an original dataset announced via ProteomeXchange.

Title	A Systematic Interrogation of MHC Class I Antigen Presentation Identifies Constitutive and Compensatory Protein Degradation Pathways
Description	Peptides presented by MHC Class I were purified from B lymphoblasts or breast cancer cell lines following protein degradation pathway perturbations. Approximately 1E8 total cells were used for each experiment.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_06:57:26.814.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Brett Lomenick
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-09 02:35:37	ID requested
1	2023-08-02 22:49:05	announced
⏵ 2	2023-11-14 06:57:27	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: autophagy,MHC Class I, neddylation, proteasome, ubiquitin, VCP, immunopeptidome, p97

Tsui-Fen Chou
contact affiliation	Proteome Exploration Laboratory Beckman Institute California Institute of Technology Pasadena, CA 91125
contact email	tfchou@caltech.edu
lab head
Brett Lomenick
contact affiliation	Caltech Proteome Exploration Lab
contact email	lomenick@caltech.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD032167

PRIDE project URI

• PRIDE
  1. PXD032167
     1. Label: PRIDE project
     2. Name: A Systematic Interrogation of MHC Class I Antigen Presentation Identifies Constitutive and Compensatory Protein Degradation Pathways