PXD032154

PXD032154 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human atrial tissue modification of Lysine 2-hydroxyisobutyrylation
Description	The role of modification of histone lysine 2-hydroxyisobutyrylation in atrial fibrillation is unclear and we hence explored the role of 2-hydroxyisobutyrylation in atrial fibrillation. Tandem Mass Tag proteomics method and other verification technologies in tissues and cells identified the protein profiles and the regulation of 2-hydroxyisobutyrylation sites. The atrial tissue of the patients with atrial fibrillation has significant differences in modification of 2-hydroxyisobutyrylation compared to that in sinus rhythm.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_08:49:30.860.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hai-Tao Hou
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	crotonylated L-lysine
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-09 02:20:34	ID requested
⏵ 1	2025-05-06 08:49:31	announced

Publication List

Hou HT, Wang XC, Chen HX, Wang J, Yang Q, He GW, channel function in the atrium from patients with atrial fibrillation. Cell Commun Signal, 23(1):117(2025) [pubmed]
10.1186/s12964-025-02108-z;

Hou HT, Wang XC, Chen HX, Wang J, Yang Q, He GW, channel function in the atrium from patients with atrial fibrillation. Cell Commun Signal, 23(1):117(2025) [pubmed]

10.1186/s12964-025-02108-z;

Keyword List

submitter keyword: Post-translational modification, human, 2-hydroxyisobutyrylation

submitter keyword: Post-translational modification, human, 2-hydroxyisobutyrylation

Contact List

Hou Hai Tao
contact affiliation	Institute of Cardiovascular Diseases & Department of Cardiovascular Surgery, TEDA International Cardiovascular Hospital, Tianjin University & Chinese Academy of Medical Sciences, Tianjin, China.
contact email	hhtpk007@163.com
lab head
Hai-Tao Hou
contact affiliation	Teda International Cardiovascular Hospital
contact email	hhtpk007@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD032154
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD032154

PRIDE project URI

Repository Record List

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