PXD032086

PXD032086 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	N-terminal processing of beta and gamma actin in human platelets
Description	Actin is one of the most essential and abundant intracellular proteins, playing an essential physiological role as the major constituent of the actin cytoskeleton. Two cytoplasmic actins, beta- and gamma-actin, are encoded by different genes, but their amino acid sequences differ only by four conservative substitutions at the N-terminus, making it very difficult to dissect their individual regulation in vivo. The majority of actins are N-terminally acetylated, following the removal of N-terminal Met. Here, we analyzed beta and gamma cytoplasmic actin N-termini in different actin preparations.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:33:33.230.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dawei Dong
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-05 12:16:38	ID requested
1	2023-03-11 02:59:00	announced
⏵ 2	2023-11-14 07:33:34	announced	2023-11-14: Updated project metadata.

Publication List

Chen L, Vedula P, Tang HY, Dong DW, Kashina AS, Differential N-terminal processing of beta and gamma actin. iScience, 25(10):105186(2022) [pubmed]

Chen L, Vedula P, Tang HY, Dong DW, Kashina AS, Differential N-terminal processing of beta and gamma actin. iScience, 25(10):105186(2022) [pubmed]

Keyword List

submitter keyword: actin,human, platelet

submitter keyword: actin,human, platelet

Contact List

Anna Kashina
contact affiliation	University of Pennsylvania
contact email	akashina@upenn.edu
lab head
Dawei Dong
contact affiliation	University of Pennsylvania
contact email	dawei.w.dong@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD032086
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD032086

PRIDE project URI

Repository Record List

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