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PXD031865

PXD031865 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEffect of low levels of fluoride in the islets of NOD mice: integrative morphological, immunohistochemical and proteomic analyses
DescriptionFluoride (F) is used in dentistry, in therapeutic doses, to prevent dental caries. Recently, animal studies have suggested that in low doses, F might reduce glucose and be beneficial in the prophylaxis of diabetes, but the involved mechanisms are still unknown. The present study evaluated changes in the pancreatic islets of NOD mice exposed to low dose of F, using morphological, immunohistochemical and proteomic tools.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:55:31.018.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJuliana Trevizol
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentXevo G2 Tof; nanoACQUITY UPLC
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-02-24 01:05:16ID requested
12023-07-20 11:09:23announced
22023-11-14 09:03:15announced2023-11-14: Updated project metadata.
32024-10-22 05:55:31announced2024-10-22: Updated project metadata.
Publication List
Trevizol JS, Dionizio A, Delgado AQ, Ventura TMO, Ribeiro CFDS, Ribeiro L, Buzalaf NR, Cestari TM, Magalh, ã, es AC, Suzuki M, Bosqueiro JR, Buzalaf MAR, Metabolic effect of low fluoride levels in the islets of NOD mice: integrative morphological, immunohistochemical, and proteomic analyses. J Appl Oral Sci, 31():e20230036(2023) [pubmed]
10.1590/1678-7757-2023-0036;
Keyword List
submitter keyword: proteomics, fluoride, islet, NOD, diabetes
Contact List
Juliana Trevizol
contact affiliationBauru School of Dentistry, University of São Paulo, Bauru, Brazil
contact emailjulianatrevizol@gmail.com
lab head
Juliana Trevizol
contact affiliationPhD student at University of São Paulo
contact emailjulianatrevizol@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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