PXD031827

PXD031827 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cross-link mass spectrometry reveals conformational changes within the N lobe and the activation loop of PDK1 upon dimerization
Description	Cross-linking mass spectrometry analysis of the PDK1 kinase domain dimer that undergoes trans-autophosphorylation.
HostingRepository	PRIDE
AnnounceDate	2022-05-20
AnnouncementXML	Submission_2022-05-20_07:13:11.418.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dorothea Anrather
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos; Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-02-22 08:48:48	ID requested
⏵ 1	2022-05-20 07:13:12	announced

Publication List

Levina A, Fleming KD, Burke JE, Leonard TA, Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation. Nat Commun, 13(1):1874(2022) [pubmed]

Levina A, Fleming KD, Burke JE, Leonard TA, Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation. Nat Commun, 13(1):1874(2022) [pubmed]

Keyword List

submitter keyword: PDK1, kinase, dimerization, phosphorylation, PIP3

submitter keyword: PDK1, kinase, dimerization, phosphorylation, PIP3

Contact List

Thomas A. Leonard
contact affiliation	Department of Structural and Computational Biology, Max Perutz Labs, Medical University, Vienna Biocenter, Vienna, Austria
contact email	thomas.leonard@meduniwien.ac.at
lab head
Dorothea Anrather
contact affiliation	Max Perutz Labs, Mass Spectrometry Facility, University of Vienna
contact email	dorothea.anrather@univie.ac.at
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD031827
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD031827

PRIDE project URI

Repository Record List

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