PXD031817

PXD031817 is an original dataset announced via ProteomeXchange.

Title	histone post-translational modification during Plasmodium falciparum gametocyte development
Description	Histone post-translational modifications (PTMs) play an essential role in epigenetic gene regulation. The Plasmodium falciparum genome encodes canonical and variant histones and a collection of conserved enzymes for histone PTMs and chromatin remodeling. Herein, we characterized the P. falciparum histone PTMs during the development of gametocytes, the obligatory for parasite transmission, we extracted histones from the early (day 4), middle (day 8), and late (day 12) stages of gametocytes, and analyzed them by advanced mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2022-09-14
AnnouncementXML	Submission_2022-09-14_09:01:10.930.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD031817
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	JUN MIAO
SpeciesList	scientific name: Plasmodium falciparum 3D7; NCBI TaxID: 36329;
ModificationList	methylated residue; ubiquitination signature dipeptidyl lysine; phosphorylated residue; acetylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2022-02-21 14:29:15	ID requested
⏵ 1	2022-09-14 09:01:11	announced

Shrestha S, Lucky AB, Brashear AM, Li X, Cui L, Miao J, Gametocyte Development. J Proteome Res, 21(8):1857-1867(2022) [pubmed]

submitter keyword: histone, malaria, gametocyte, Plasmodium falciparum

Jun Miao
contact affiliation	Dept of Internal Medicine, Morsani College of Medicine, University of South Florida
contact email	jmiao1@usf.edu
lab head
JUN MIAO
contact affiliation	University of Sourth Florida
contact email	jmiao1@usf.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD031817
     1. Label: PRIDE project
     2. Name: histone post-translational modification during Plasmodium falciparum gametocyte development