<<< Full experiment listing

PXD031755

PXD031755 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMolecular basis of nuclear mRNA recognition and packaging
DescriptionNewly made messenger RNAs are processed and packaged into compact ribonucleoprotein complexes (mRNPs) and recognized by the essential transcription-export complex (TREX) for nuclear export. However, the mechanisms of mRNP recognition, compaction, and three-dimensional organization are poorly understood. Here we perform crosslinking MS on Sulfo-SDA crosslinked endogenous ribonucleoprotein complexes (mRNPs). These have been enriched through a pulldown of THOC1-3C-GFP.
HostingRepositoryjPOST
AnnounceDate2023-01-31
AnnouncementXMLSubmission_2023-01-31_07:25:56.380.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD031755
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFrancis O'Reilly
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-02-20 16:13:29ID requested
12023-01-31 07:25:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Crosslinking MS, Human, TREX, endogenous, RNP
Contact List
Juri Rappsilber
lab head
Francis O'Reilly
contact affiliationNCI-NIH
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001488/