⮝ Full datasets listing

PXD031749

PXD031749 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLipid mediated–phase separation of AGO proteins on the ER controls nascent peptide ubiquitination
Descriptionwe sought to determine whether dmAGO1 and Ltn1 share common ubiquitinated nascent peptide targets. For this purpose, we performed the UBA bead-based immunoprecipitation followed by mass spec experiments to identify the ubiquitinated nascent peptide targets of dmAGO1 and Ltn1, respectively. In this assay, we used four different samples including gfp knockdown, vcp knockdown, vcp-ago1 double knockdown and vcp-ltn1 double knockdown S2 cells.
HostingRepositoryiProX
AnnounceDate2022-02-18
AnnouncementXMLSubmission_2023-12-24_20:39:10.681.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYajie Gao
SpeciesList scientific name: Drosophila melanogaster; NCBI TaxID: 7227;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-02-17 22:42:17ID requested
12022-02-17 22:42:58announced
22023-12-24 20:39:11announced2023-12-25: Update information.
Publication List
Gao Y, Zhu Y, Wang H, Cheng Y, Zhao D, Sun Q, Chen D, Lipid-mediated phase separation of AGO proteins on the ER controls nascent-peptide ubiquitination. Mol Cell, 82(7):1313-1328.e8(2022) [pubmed]
Keyword List
submitter keyword: AGO1, ER, Nascent peptide, Drosophila, Lipidbinding
Contact List
Dahua Chen
contact affiliationInstitute of Biomedical Research, Yunnan University
contact emailchendh@ioz.ac.cn
lab head
Yajie Gao
contact affiliationInstitute of Biomedical Research, Yunnan University
contact emailgaoyajie@ynu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI