PXD031714

PXD031714 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Nuclear F-actin Assembly on Damaged Chromatin is Regulated By DYRK1A and Spir1 Phosphorylation
Description	The uploaded data are described within "DYRK1A promotes nuclear F-actin assembly to effect DSB repair metabolism". Peptides from RPE1 epithelial cells with either, over expression of DYRK1A, normal expression of DYRK1A, or knockout of DYRK1A were labeled with TMTpro-16 reagents and phosphopeptides enriched by TiO2 and Fe-NTA resins.
HostingRepository	PRIDE
AnnounceDate	2024-07-19
AnnouncementXML	Submission_2024-07-19_11:08:22.022.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kirk West
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-02-16 04:44:14	ID requested
⏵ 1	2024-07-19 11:08:22	announced

Publication List

10.1093/nar/gkae574;
Li J, Xiong N, West KL, Leung M, Ching YP, Huang J, Yuan J, Yu CH, Leung J, Huen M, Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation. Nucleic Acids Res, 52(15):8897-8912(2024) [pubmed]

10.1093/nar/gkae574;

Li J, Xiong N, West KL, Leung M, Ching YP, Huang J, Yuan J, Yu CH, Leung J, Huen M, Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation. Nucleic Acids Res, 52(15):8897-8912(2024) [pubmed]

Keyword List

submitter keyword: DYRK1A
DSB repair
Spir1
DSB mobility
Actin Dynamics

submitter keyword: DYRK1A

DSB repair

Spir1

DSB mobility

Actin Dynamics

Contact List

Justin Wai
contact affiliation	Department of Radiation Oncology, University of Texas Health Science Center at San Antonio
contact email	JWLeung@uams.edu
lab head
Kirk West
contact affiliation	University of Arkansas for Medical Sciences
contact email	kwest@uams.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD031714
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD031714

PRIDE project URI

Repository Record List

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