PXD031704

PXD031704 is an original dataset announced via ProteomeXchange.

Title	sAPP a neuroprotective protein in the brain has widespread effects on the proteome of human cortical neurons related to memory mechanisms.
Description	Human glutamatergic neurons in culture were exposed to 1 nM secreted amyloid precursor protein alpha over a time course (0, 2, 6 and 24 h) and changes in the proteome were identified with SWATH-MS.
HostingRepository	PRIDE
AnnounceDate	2022-04-04
AnnouncementXML	Submission_2022-04-03_16:01:39.817.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Torsten Kleffmann
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2022-02-16 02:46:01	ID requested
⏵ 1	2022-04-03 16:01:40	announced

Dataset with its publication pending

submitter keyword: APP, sAPPa, Alzheimer’s disease, human neuron, proteome.

Warren Tate
contact affiliation	Department of Biochemistry, University of Otago, New Zealand
contact email	warren.tate@otago.ac.nz
lab head
Torsten Kleffmann
contact affiliation	Department of Biochemistry, University of Otago
contact email	torsten.kleffmann@otago.ac.nz
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/04/PXD031704

PRIDE project URI

• PRIDE
  1. PXD031704
     1. Label: PRIDE project
     2. Name: sAPP a neuroprotective protein in the brain has widespread effects on the proteome of human cortical neurons related to memory mechanisms.