PXD031636

PXD031636 is an original dataset announced via ProteomeXchange.

Title	In-depth Profiling and Quantification of the lysine acetylome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer
Description	This is supplemental data of “ In-depth Profiling and Quantification of the lysine acetylome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer ” project. In this data, we employed an integrated proteomics and acetylomics strategy to characterize of three Huh7 cells (NC1, NC2, NC3) and three SIRT2 overexpression cells (SIRT2-1, SIRT2-2, SIRT2-3) with 4D proteomics technology. Proteomics analysis identified a total of 5052 proteins, of which 4255 proteins were quantified across all samples. A total of 5307 acetylation sites on 2094 proteins were identified.
HostingRepository	PRIDE
AnnounceDate	2022-07-02
AnnouncementXML	Submission_2022-07-02_00:03:39.661.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	jia xu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-02-13 12:57:34	ID requested
⏵ 1	2022-07-02 00:03:40	announced

Xu J, Guan X, Jia X, Li H, Chen R, Lu Y, In-depth Profiling and Quantification of the Lysine Acetylome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer. Mol Cell Proteomics, 21(8):100255(2022) [pubmed]

submitter keyword: acetylomics, cellular metabolism, hepatocellular carcinoma, non-histone, PASEF, proteomics, SIRT2, timsTOF pro.

Ruibing Chen
contact affiliation	School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China
contact email	rbchen@tju.edu.cn
lab head
jia xu
contact affiliation	tianjin university
contact email	564929283@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD031636

PRIDE project URI

• PRIDE
  1. PXD031636
     1. Label: PRIDE project
     2. Name: In-depth Profiling and Quantification of the lysine acetylome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer