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PXD031634

PXD031634 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMultifactorial remodeling of the cancer immunopeptidome by interferon gamma
DescriptionIn this study we combined previous transcriptomics and immunopeptidomics data with new proteomics data from untreated and IFNg-treated CRC PDOs to dissect mechanisms that lead to remodeling of the immunopeptidome through IFNg treatment (this is from the paper introduction, let me know if it needs any stylistic changes). ยท Experiment description: The cells were grown in DMEM/F12 media with 20% fetal bovine serum, 1X Glutamax, 100 units/ml penicillin/streptomycin and 2% matrigel, and treated with 600ng/mL IFNg for 48 hours before harvesting. Cells were washed twice with ice-cold PBS then snap-frozen.
HostingRepositoryPRIDE
AnnounceDate2023-09-29
AnnouncementXMLSubmission_2023-09-29_09:43:14.444.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJamesWright
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-02-13 12:37:35ID requested
12023-09-29 09:43:14announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, Immuno, TMTpro, Cancer, HCD
Contact List
JyotiChoudhary
contact affiliationThe Institute of Cancer Research
contact emailjyoti.choudhary@icr.ac.uk
lab head
JamesWright
contact affiliationThe Institute of Cancer Research
contact emailjames.wright@icr.ac.uk
dataset submitter
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Dataset FTP location
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