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PXD031535

PXD031535 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGlobal proteome of Atg5flox:Slc32a1-Cre:tdTomato FACS sorted WT and KO neurons
DescriptionThe experiment was performed to identify autophagy targets in wildtype and autophagy-deficient forebrain inhibitory neurons. Therefore, neurons were isolated from the cortex, hippocampus and striatum of 2-3 weeks old Atg5flox/flox:Slc32a1-Cretg/wt:tdTomato+ (KO) and Atg5wt/wt:Slc332a1-Cretg/wt:tdTomato+ (WT) mice. Neurons in suspension were FACS sorted and inhibitory forebrain neurons expressing tdTomato were forwarded to global proteome analysis assessed by LC-MS/MS.
HostingRepositoryPRIDE
AnnounceDate2022-11-15
AnnouncementXMLSubmission_2022-11-15_00:34:59.671.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPreranaWagle
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-02-09 05:22:52ID requested
12022-11-15 00:35:00announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: ATG5 KO, in-vivo proteome, Neurons,Autophagy
Contact List
N.L.Kononenko
contact affiliationCECAD Excellence Center, University of Cologne, Germany, D-50931 Center for Physiology and Pathophysiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany, D-50931
contact emailn.kononenko@uni-koeln.de
lab head
PreranaWagle
contact affiliationCECAD Research Center
contact emailproteomics-facility@uni-koeln.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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