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PXD031273

PXD031273 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAndrogen receptor RIME in prostate cancer cells
DescriptionAndrogen receptor (AR) is a master transcription factor that drives prostate cancer (PCa) development and progression. Alterations in the expression or activity of AR coregulators significantly impact the disease's outcome. To identify all the essential components of the AR coregulator complex, we utilized a proteomic approach called rapid immunoprecipitation of endogenous proteins (RIME) to systematically identify all coregulator proteins of the AR interactome in PCa cells.
HostingRepositoryPRIDE
AnnounceDate2022-07-12
AnnouncementXMLSubmission_2022-07-12_09:11:52.140.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmittermi chen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-26 12:21:10ID requested
12022-07-12 09:11:52announced
Publication List
Chen M, Lingadahalli S, Narwade N, Lei KMK, Liu S, Zhao Z, Zheng Y, Lu Q, Tang AHN, Poon TCW, Cheung E, TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation. EMBO Rep, 23(8):e53468(2022) [pubmed]
Keyword List
submitter keyword: androgen receptor, prostate cancer, RIME, cofactors
Contact List
Edwin Chong Wing CHEUNG
contact affiliationFaculty of Health Sciences, University of Macau, Macau, China
contact emailECheung@um.edu.mo
lab head
mi chen
contact affiliationFaculty of Health Sciences, University of Macau, Macau, China
contact emailmchen0817@live.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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