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PXD031270

PXD031270 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRaw data for "Dynamic mitochondrial proteome under polyamines treatment in cardiac aging"
DescriptionIn this study, we found that spermine (Spm) and spermidine (Spd) injection for 6 weeks could prevent 24-month old rats heart dysfunction,improve mitochondrial function and down-regulate apoptosis. Using iTRAQ tools, we identify 75 mitochondrial proteins of statistically significant alteration in aging hearts, which mainly participate in important mitochondrial physiological activity, such as metabolism, translation, transport, apoptosis and oxidative phosphorylation.
HostingRepositoryPRIDE
AnnounceDate2022-05-20
AnnouncementXMLSubmission_2022-05-20_06:02:12.428.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHao Zhang
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-26 12:17:03ID requested
12022-05-20 06:02:14announced
Publication List
Zhang H, Yan M, Liu T, Wei P, Chai N, Li L, Wang J, Yu X, Lin Y, Qiu B, Zhao Y, Dynamic Mitochondrial Proteome Under Polyamines Treatment in Cardiac Aging. Front Cell Dev Biol, 10():840389(2022) [pubmed]
Keyword List
submitter keyword: mitochondrial proteome
Contact List
Yajun Zhao
contact affiliationDepartment of Pathophysiology, Harbin Medical University, Harbin, China
contact email100070@hrbmu.edu.cn
lab head
Hao Zhang
contact affiliationHarbin Medical University
contact emailzh_prince@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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